The gut microbiome is key in the connection between our digestive system and our brain. The signaling that occurs between these two systems is often mediated by metabolites and other compounds produced by the gut microbiome. This signaling could result in a more relaxed and good control of the sleep cycle or it could adversely affect it. Simple Slumber helps support a balance signaling between the gut and the brain and promotes peaceful, sound sleep.

Simple Slumber increases melatonin production as well as its precursor serotonin. It also activates opiate receptors for better sleep as well as the production of antioxidants such as reduced glutathione and anti-inflammatory substances such as butyrate.

Good, sound sleep involves understanding how stress, diet and environmental factors affect body’s metabolism and quality of sleep. Steps to improve sleep often include lifestyle changes in exercise and diet. One of the easiest ways to support a healthy sleep-wake cycle is to restore balance in your gut microbiome with probiotics that target the proper signaling from the gut to the brain. Our signature blend has been created to release compounds and hormones that promote sound, undisturbed sleep.

When the gut lining is compromised, bacterial by products (metabolites) can enter the body and induce inflammation that directly affect how you sleep. You’ll find two proprietary strains in our six-strain formula that work in harmony. This formula was designed to help the body produce metabolites that promote sleep and relaxation, reduce inflammation and decrease the pathogen load. Together, these six bacteria form a stable, sustainable bacterial community and help restore a healthy gut microbiome and more importantly, promote healthy and sound sleep.

Here are some of the key strains and benefits that differentiate our formula:

Bacillus subtilis (DE111®): promotes a healthy microbiome for enhanced immune function and disease control by producing of bacteriocins. It also helps maintain healthy levels of antioxidants and metabolites to promote sleep.

Bifidobacterium longum: improves sleep and mood quality in humans, especially during periods of stress. It produces metabolites to restore gut health, reduce oxidative stress, and stimulate the sleep centers of the brain.

Lactobacillus plantarum (TBC0036™): Genetic analysis proves this organism produces metabolites to promote a good sleep quality by expanding the blood vessels, thus, increasing blood flow and the flux of sleep-inducing hormones. It also produces melatonin and metabolizes fiber and other carbohydrates to produce anti-inflammatory substances.

Lactobacillus acidophilus (DDS®1) helps reduce sleep-perturbation markers of stress and inflammation, thus, reducing circadian disruption and promoting sleep. It persists in the gut long-term and stabilizes the sleep cycle.

Lactobacillus casei: Improves sleep under psychological stress, by reducing anxiety and helps stabilize a healthy gut microbiome. When blended with the other strains in this formula, it contributes to the production of serotonin, melatonin and antioxidants.

Leuconostoc mesenteroides (TBC0037™): converts sugars into mannitol, produces anti-inflammatory substances, protects the gut lining and makes vitamin B12. B12 keeps nerves and blood cells healthy and helps with normal, healthy sleep. This strain produces melatonin, antioxidants and anti-inflammatory substances to counteract the adverse effects of stress.

Our formulas are balanced for sustained action, which means they work longer and are stronger. Restore the balance of bacteria in your gut and rediscover your best health.